Central regions | Technology & innovation

Researchers show how to step up cancer therapy efficacy

27 Feb '17
Researchers from Russias Moscow Lomonosov State University (MSU) and their Swedish colleagues have provided enough evidence to show that denying cancer cells access to nutrient substances could impact therapy both negatively and positively, depending on the type of an anti-tumor drug.

The scientists have published an English-language article on this research in Biochimica et Biophysica Acta Molecular Cell Research.

Cancer cells grow very fast and need much energy to sustain growth, consuming glucose in much greater quantities than healthy cells. However, if theres not enough glucose for them to feed on, some of the cancer cells begin devouring an amino acid called glutamine.

According to Vladimir Gogvadze, a senior research fellow at MSUs apoptosis study laboratory, the international team has now proved that depending on different anti-tumor drugs, depriving cancer cells of access to glutamine can stimulate their death in some instances and prevent it in some others. So, its now clear that a physician should think twice before combining anti-tumor drug therapy with glutamine metabolism (TTFA mitochondrial complex II) inhibitors.
Publish in Twitter
Write to Facebook
Google Buzz
Write to LiveJournal
Show in MM
Share MK
COMMENT ON THIS STORY
Find Related Content

Locations: Moscow

Tags: cancer (63) / MSU (38) / anti tumor drug (1) / glutamine (0) /

Latest News: Central regions
16 Jan '18 | Finance, business | Technology & innovation
15 Jan '18 | Technology & innovation
11 Jan '18 | Finance, business | Technology & innovation
9 Jan '18 | Technology & innovation | Retail, FMCG
 

Feature stories

21 Nov '17
Russian scientists have come up with what they say is...
7 Sep '17
26 Jul '17
Scientists at Tomsk Polytechnic (TPU) in Siberia have...
Search (News archive - 21208)
Advertising
Independent Software Developers Forum
Advertising
Marchmont News

Latest News

23 Jan '18
Researchers at the North-Eastern Federal University...
22 Jan '18
A scientific team in Novosibirsk, in Siberia, has...
19 Jan '18
Scientists in Samara have come up with a new method...

Most read stories from last week

23 Jan '18
Researchers at the North-Eastern Federal University...
22 Jan '18
A scientific team in Novosibirsk, in Siberia, has...